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Chelsea Fertility NYC Blog

You can’t teach an old dog new tricks …oh, yes you can!

by Chelsea Fertility NYCPosted in Dr. Gindoff, IVFApril 27th, 2017

From Dr. Paul Gindoff of Chelsea Fertility New York City:

I finished my fellowship in the late 1980s around the time when in vitro fertilization (IVF) treatment was just being introduced as a mainstream modality to treat female infertility. IVF treatment and management has changed significantly over the past twenty-five years.

At first, we started transferring embryos on day 2 or day 3 after egg retrieval, and these were always fresh transfers. Then, we developed freezing techniques, but embryo survival wasn’t refined enough to give desired results. Using a donor egg was the safety net for many hard-core cases and for recurrent pregnancy loss that could not be treated successfully.

Only with the establishment of a new freezing technique, vitrification, and advanced culturing of embryos to day 5 blastocyst, had the system really evolved to allow dramatic improvements in pregnancy rates and implantation for most patients.

This sounds like a watershed event, but the advancement with most impact has been PGS, pre-implantation genetic screening.

With trophoblast biopsy of blastocyst embryos and PGS, the filtering and selection process is so refined that only one vetted normal embryo will lead to a pregnancy in over 60% of cases on average at any age. This can now be combined with freeze-thaw embryo transfer to optimize the uterine receptivity and environment as “THE” state-of –“ART” treatment.

At Chelsea Fertility NYC, we have shifted to this latter modality in a huge way and it works beautifully.