The Overlap Between PCOS and Endometriosis: Can You Have Both?

Polycystic ovary syndrome (PCOS) and endometriosishttp:// are two of the most common reproductive conditions affecting women of reproductive age. Although they are distinct conditions, a person can have both at the same time.
What is PCOS?
PCOS is primarily a hormonal condition in which the ovaries often produce higher levels of androgens, sometimes referred to as “male hormones.” This hormonal imbalance can interfere with normal ovulation. In a typical cycle, one egg matures and is released from the ovary. With PCOS, ovulation may occur irregularly or not at all, which can make it more difficult to conceive.
What is Endometriosis?
Endometriosis affects fertility through a different pathway. The endometrium is the tissue that lines the inside of the uterus and sheds during a menstrual period. In endometriosis, tissue similar to the uterine lining grows outside the uterus, often on the ovaries, fallopian tubes, or other structures in the pelvis. Unlike the uterine lining, this tissue has no way to exit the body during a menstrual cycle. Over time, this can lead to inflammation, cyst formation, and scar tissue that may affect how easily an egg is released, fertilized, or implanted.
Can Someone Have Both PCOS and Endometriosis?
Although these conditions develop through different biological processes, someone can have both PCOS and endometriosis at the same time.
When both conditions are present, symptoms may overlap or appear more complex. For example, irregular cycles associated with PCOS may occur alongside pelvic pain or heavy periods that are sometimes linked to endometriosis.
In some cases, one condition may be identified first, while the other is discovered later when symptoms or infertility persist.
How Fertility Treatment May Change With a Dual Diagnosis
When both PCOS and endometriosis are present, treatment strategies often need to address multiple factors affecting fertility.
For individuals with PCOS, fertility treatment typically focuses on improving ovulation, which may include medications that help stimulate egg release. However, when endometriosis is also present, these medication protocols may be adjusted or more closely monitored to avoid worsening inflammation or other symptoms associated with endometriosis.
Endometriosis can also create additional challenges to conception. For example, scar tissue or inflammation around the fallopian tubes may interfere with fertilization. In some cases, surgical treatment may be recommended to remove endometriosis lesions or scar tissue before attempting pregnancy. If pregnancy is still difficult to achieve, your provider may recommend in vitro fertilization (IVF), in which eggs are retrieved from the ovaries and fertilized with sperm in a laboratory before the resulting embryo is transferred into the uterus.
Lifestyle strategies may also play a supportive role for individuals managing both conditions. Approaches that help stabilize blood sugar levels, reduce inflammation, and support hormone balance, such as a balanced diet and regular physical activity, may complement medical treatment.
While having both PCOS and endometriosis can make conception more complex, many individuals still go on to have successful pregnancies with treatment plans that are carefully tailored to their specific needs.
Why a Comprehensive Fertility Evaluation Matters
Because PCOS and endometriosis can affect fertility in different ways and sometimes occur together, a comprehensive fertility evaluation can be an important step in identifying the full picture of a patient’s reproductive health.
Testing may include hormone evaluations, imaging studies, and other assessments that help determine how the ovaries, uterus, and surrounding reproductive structures are functioning. Understanding the underlying causes of fertility challenges allows physicians to recommend treatment strategies based on each patient’s unique needs.
At Chelsea Fertility NYC, fertility specialists take a comprehensive approach to diagnosing and treating complex reproductive conditions, including cases where PCOS and endometriosis may overlap. If you’ve been diagnosed with one of these conditions or are experiencing symptoms that may suggest an underlying fertility issue, scheduling a consultation can be an important first step toward understanding your options and developing a plan for moving forward.